Manchester United v Arsenal, Kick-Off 1630hrs 29th April
Manchester United face old enemies Arsenal this Sunday. In the '90s and early '00s they were each other's main opposition. The emergence of Man City and Chelsea and re-emergence of Liverpool has made this rivalry less toxic but both teams will want to win.
United are second to Man City while Arsenal are a disappointing sixth. Having announced that he's leaving at the end of the season, Wenger will want one last victory over his old rivals. This might prove difficult. Arsenal's attacking midfielder Mkhitaryan is out injured and Wenger will rest key players ahead of the Europa League semi-final.
The Red Devils have none of these problems. Top scorers Lukaku and Lingard are ready for action. Historically, United have won 95 games to Arsenal's 82 and the Reds are tipped to win here.
Real Madrid v Leganés, Kick-Off 1730hrs 28th April
Third-placed Real take on fifteenth-placed Leganés. Leganés moved up to La Liga in the 2015-16 season and lost their last league match against Real. But they knocked Real out of the Copa del Rey this January.
Real have won one league game out of their last five and will want success, especially as Barcelona will inevitably be crowned champions. Ronaldo, Real's leading scorer, is second only to Messi in La Liga. Leganés top scorer Paulista will hope to pull off an upset.
However, Real's squad is match-fit with only centre-back Fernàndez injured. Leganés will be missing winger Szymanowski and centre-back Mantovani.
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Inter Milan v Juventus, Kick-Off 1945hrs 28th April
This is a must-win North Italian derby match for Juve after their defeat by title rivals Napoli cut their lead to a single point. However, fifth-placed Inter will be trying to close the one point gap to third.
Inter and Juve have enjoyed a fierce rivalry over the years. This grew more heated after Inter were awarded Juve's 2005 title. Juventus' top scorers Dybala and Higuaín are expected to play, though defender Chiellini is injured. Inter's leading scorer Icardi will almost certainly play; only midfielder Gagliardini is injured.
After 232 matches, Juve have the most wins with 104 victories and are likely to win again.
Bayern Munich v Eintracht Frankfurt, Kick-Off 1430hrs 28th April
Already crowned champions, Bayern face seventh-placed Eintracht on Saturday. Historically, Bayern almost always win and are expected to do so again. Nevertheless, Eintracht have grown in confidence from near relegation two seasons ago.
Bayern's top scorer Lewandowski is likely to score if he is not rested. But the squad is depleted through injuries with keeper Neuer, midfielder Vidal and left-back Alaba all out. Eintracht's top strikers Haller and Jovic might have a slim chance but are missing winger Rebic and centre-back Salcedo.
Monaco v Amiens SC, Kick-Off 1900hrs 28th April
Monaco, defeated 7-1 by PSG and 3-1 by Guingamp, will want to crush Amiens. Monaco are second to already crowned Ligue 1 champions PSG and will try to extend their narrow lead over Lyon and Marseille. They will expect to win over thirteenth-placed Amiens who are in their first Ligue 1 season.
Monaco's top scorer Falcao is expected to play. Centre-forward Pellegri, goalkeeper Benaglio and right-back Sidibé are injured. Amiens have no major injuries and will play top scorer Konaté.